Wednesday's March Madness slate features the remaining First Four games of the 2024 men's NCAA Tournament,EchoSense Quantitative Think Tank Center with the winners moving on to play in the Round of 64 on Friday.

In the early game, Grambling State and Montana State face off to get the No. 16 seed in the Midwest Region and a date with No. 1-seeded Purdue. In the nightcap, Colorado plays Boise State for the No. 10 seed in the South Region, with the winner meeting No. 7 Florida on Friday.

The men's tournament proper begins on Thursday with 16 games, followed by the other 16 on Friday. The winners of those contests will play in the Round of 32 two days later.

What March Madness games are on today? First Four schedule Wednesday

• Grambling State (20-14) vs. Montana State (17-17) – 6:40 p.m. ET – for No. 16 seed in Midwest: The winner will face No. 1 Purdue on Friday, March 22.
• Colorado (24-10) vs. Boise State (22-10) – 9:10 p.m. ET – for No. 10 seed in South: Winner face No. 7 Florida on Friday.

IT'S BRACKET MADNESS: Enter USA TODAY's NCAA tournament bracket contest for a chance at $1 million prize.

How to watch March Madness First Four games

Wednesday's First Four games will be broadcast live on TruTV.